| Название | Игры |
||
| Samurai Aces | 2 | ||
| Samurai Shodown | 3 | ||
| Samurai Warriors | 4 | ||
| Science Adventure | 7 | ||
| Scribblenauts | 5 | ||
| SD Gundam G Generation | 2 | ||
| Season Match | 2 | ||
| SEGA AGES | 13 | ||
| Sega All-Stars | 2 | ||
| SEGA Classics | 16 | ||
| Senran Kagura | 5 | ||
| Sense | 2 | ||
| Serial Cleaner | 2 | ||
| Shadowrun | 4 | ||
| Shantae | 10 | ||
| Sherlock Holmes | 3 | ||
| Shinobi | 2 | ||
| Shovel Knight | 4 | ||
| Shred | 2 | ||
| Skautfold | 2 | ||
| Skies | 2 | ||
| Sky Force | 2 | ||
| Skylanders | 11 | ||
| Smoots | 2 | ||
| Sniper Elite | 4 | ||
| SNK | 2 | ||
| Sonic | 27 | ||
| South Park | 3 | ||
| Space Invaders | 2 | ||
| Sparkle (10tons Ltd) | 2 | ||
| Spelunky | 2 | ||
| Spider-Man | 3 | ||
| Spirit Hunter | 3 | ||
| SpongeBob SquarePants | 5 | ||
| Spot The Difference | 2 | ||
| Star Ocean | 2 | ||
| Star Wars | 18 | ||
| Star Wars Jedi Knight | 2 | ||
| SteamWorld | 11 | ||
| Steins;Gate | 2 | ||
| Steven Universe | 2 | ||
| Story of Seasons | 4 | ||
| Storybook | 2 | ||
| Street Fighter | 4 | ||
| STRIKERS 1945 | 3 | ||
| Subnautica | 2 | ||
| Sunless | 2 | ||
| Supaplex | 6 | ||
| Super Destronaut | 2 | ||
| Super Meat Boy | 3 | ||
